BackgroundFrailty is characterised by a reduced resilience to adversity.In this analysis we examined changes in frailty hero chestnut puree in people aged 50+ before and during a period of austere public spending in England.MethodsData from the English Longitudinal Study of Ageing 2002-2018 were analysed.Associations between austerity and frailty w
Probing the dynamic activities of protein kinases in real-time in living cells constitutes a major challenge that requires specific and sensitive tools tailored to meet the particular demands associated with cellular imaging.The development of genetically-encoded and synthetic fluorescent biosensors has provided means of monitoring protein stirrup
ABSTRACT Elizabethkingia anophelis, a nonfermenting Gram-negative bacterium, causes life-threatening health care-associated infections.E.anophelis harbors multidrug resistance (MDR) genes and is intrinsically resistant to various classes of antibiotics.Outer membrane vesicles (OMVs) are secreted by Gram-negative bacteria and contain materials invol
The ASPIRE-to-Excellence Academy was recently founded at the 2015 Association for Medical Education in Europe (AMEE) stirrup extender western conference in Glasgow.The academy is new pillar of the ASPIRE-to-Excellence initiative by AMEE, which aims at promoting and encouraging medical schools in achieving excellence in the categories of assessment,
BackgroundAtrial fibrillation (AF) is a major risk factor for ischemic stroke unless treated with an anticoagulant.Detecting AF can be difficult because AF is often paroxysmal and asymptomatic.The aims of this study were to develop a screening model to detect AF in a primary healthcare setting and to initiate oral anticoagulant therapy in high-risk